The document provides guidance on skinning and customizing a SharePoint 2010 site. It recommends starting by designing the skin in a graphic designer, then converting it to HTML. Key steps include identifying common regions for master pages, editable regions, and menus/submenus. The document warns that skinning SharePoint can cause headaches and lists resources for skinning techniques using SharePoint Designer or Visual Studio, including creating new master pages and page layouts. It also provides tips on using CSS, themes, URLs and the new ribbon control in customizations.