This document discusses health technology assessment (HTA) and commissioning in the English NHS, with a focus on general practitioners (GPs). It provides background on HTA, which evaluates the clinical effectiveness and cost-effectiveness of health interventions. It also discusses key elements of the 2010 NHS reform plan and the history of GP commissioning in England since the 1990s, including GP fundholding schemes that gave GPs budgets to purchase some services. Evaluation found GPs were able to improve primary care and develop alternatives to hospital care, but faced challenges shifting resources from hospitals.