Thoracic outlet syndrome (TOS) occurs when the blood vessels or nerves in the thoracic outlet area between the neck and armpit are compressed. The thoracic outlet contains several narrow spaces through which the nerves and vessels pass. Physical therapy is the primary treatment for TOS and aims to open the spaces and correct shoulder positioning. Surgery to remove part of the first rib may be considered if physical therapy fails or for complications involving blood vessels or nerves. Proper diagnosis involves patient examination maneuvers to reproduce symptoms and imaging tests to identify anatomical abnormalities.