WebRTC will disrupt web conferencing, video conferencing, and unified communications by providing high-quality real-time audio, video, and collaboration functionality directly in web browsers without plugins. This represents a major change from current solutions that rely on proprietary desktop applications and specialized hardware. National research and education networks should track WebRTC closely, prepare users for this transition, and explore opportunities to offer new low-cost services that take advantage of WebRTC's capabilities, such as easy group conferencing and supporting remote collaboration. Trials of WebRTC solutions should begin soon to gain experience before mainstream adoption.