This document provides guidelines for submitting a physics experiment to be performed aboard the International Space Station. Experiments must adhere to safety rules, including no sharp objects, hazardous materials, or radio transmitters. Components must be contained, use only small magnets and motors, operate within certain temperature and noise levels, and fit within defined size limits. Prototypes are encouraged to demonstrate feasibility. If selected, the experiment will be adapted for spaceflight and recorded by astronauts during a 60-90 minute session.