Chemistry:Talastine
From HandWiki
Short description: Chemical compound
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| Formula | C19H21N3O |
| Molar mass | 307.397 g·mol−1 |
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Talastine (trade name Ahanon) is an antihistamine.[1]
Synthesis
The amide proton from 4-Benzylphalazone is abstracted with KOH, which is then alkylated with dimethylaminoethyl chloride.[2][3]
References
- ↑ "[Talastine (Ahanon) as a cause of allergic drug exanthema]" (in German). Dermatologische Monatschrift 176 (2–3): 111–3. 1990. PMID 1973126.
- ↑ Engelbrecht, et al., DE patent 1046625, issued 1958, assigned to VEB Deutsches Hydrierwerk Rodleben
- ↑ Engelbrecht, et al., US patent 3017411, issued 1962, assigned to VEB Deutsches Hydrierwerk Rodleben
External links
- "Talastine". Comparative Toxicogenomics Database. http://ctdbase.org/detail.go?type=chem&acc=C009376.
- Talastine at the US National Library of Medicine Medical Subject Headings (MeSH)
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