Compare the Top Email Encryption Software for Startups as of January 2026

What is Email Encryption Software for Startups?

Email encryption software ensures the confidentiality and integrity of email communications by converting messages into unreadable formats that can only be decrypted by authorized recipients. It uses encryption protocols such as S/MIME and PGP to protect sensitive information from interception, eavesdropping, and unauthorized access. The software helps organizations comply with data privacy regulations like GDPR, HIPAA, and CCPA by securing emails containing personal or financial information. Email encryption can be applied at the message level, attachment level, or entire inbox, providing versatile protection for both internal and external communications. By safeguarding email content, businesses can reduce the risk of data breaches, maintain customer trust, and avoid costly compliance fines. Compare and read user reviews of the best Email Encryption software for Startups currently available using the table below. This list is updated regularly.

  • 1
    Paubox

    Paubox

    Paubox

    Healthcare's simple, easy, and scalable way to email secure, HIPAA compliant patient information. Keeping patient data secure and remaining HIPAA compliant is a top concern for healthcare organizations, especially when it comes to email. Paubox Email Suite provides guaranteed encryption so you can rest assured your patient data is protected. Our HIPAA compliant email service removes the hassle of portals and passcodes by sending encrypted emails that can be read right in your recipient’s inbox. Healthcare email encryption is easy with our patented tools which integrate easily into your existing email system with no training necessary for employees. Paubox HIPAA compliant email service is designed to empower IT and simplify the process for end-users, making the frustrations and vulnerability of emailing PHI a thing of the past.
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    Starting Price: $29/month
  • 2
    Send It Secure

    Send It Secure

    Protected Trust

    Send and receive secure emails that enable you to meet HIPAA & GLBA compliance standards. Protected Trust Email Encryption is now Send It Secure by Protected Trust. You may know us as Protected Trust Email Encryption, or perhaps just Protected Trust. As our email encryption product has grown and our company offerings have increased, we believe it is the right time to create a new brand for our email encryption product. Our new brand comes with the product the market has learned to trust, and we welcome an even better user experience and an improved product designed to meet your needs. We are recognized as one of the most powerful encryption solutions on the market for the secure exchange of confidential data. Your trust and protecting your data are our priority. We are excited to bring you our updated email encryption solution, Send It Secure by Protected Trust.
    Starting Price: $15 per month
  • 3
    PBHS SecureMail
    Achieve and maintain data privacy compliance. PBHS Secure Mail is a mature HIPAA encrypted messaging solution for doctors, dentists, hospitals and other healthcare providers. Compliancy made easy! There is no software to install, configure or maintain. PBHS Secure Mail works on any device, from any location. It’s simple to share. Documents, Radiographs, CT Scans, and Messages are organized and available to all colleagues working on a case. Account initiation is as simple as logging in with your ADA Membership ID. Our optional Outlook Plug-in enables users to send and receive messages directly via Microsoft Outlook on your PC. Treatment Letters and private communications that are delivered from your practice management software to Outlook are now encrypted. Radiographs that are delivered from your digital x-ray systems to Outlook are now encrypted. No need to change how you email your colleagues and patients. Continue to use Outlook without violating HIPAA.
    Starting Price: $10 per month per account
  • 4
    LuxSci

    LuxSci

    Lux Scientiae

    LuxSci provides HIPAA-compliant web and email communications services. LuxSci creates uniquely secure and customizable enterprise-grade environments and solutions that enable organizations to confidently meet their specific business and security needs at scale. LuxSci’s HIPAA-compliant email and web solutions are HITRUST certified and include: • Secure High Volume Sending for delivering massive volumes of transactional and marketing emails. • Secure SMTP Connector for encrypting outbound emails sent from Microsoft 365 and Google Workspace. • Secure Email Marketing platform for creating and sending marketing campaigns with ePHI. • Secure Email Hosting for reliable and secure day-to-day business email. • Fully managed Secure Web and Database Hosting for web applications that require compliance. • Secure Forms to safely collect and store sensitive information. LuxSci provides a full suite of secure technology for companies requiring compliant web and email services.
    Starting Price: $4 per/user/month
  • 5
    MailHippo

    MailHippo

    MailHippo

    HIPAA compliant email made easy and affordable. MailHippo is the easiest way to securely send and receive sensitive information and attachments by email. There's no setup or configuration required. Just sign up and start sending and receiving HIPAA-compliant emails right away. End-to-end encryption means your sensitive emails and attachments are always secure, both in transit and at rest. MailHippo works with your current email address, and with any email provider. MailHippo looks and works great on any smartphone or tablet. Get a unique link that empowers you to receive totally-secure emails from anyone. Get our HIPAA-compliant email platform with secure encrypted email messaging for FREE during our limited-time Beta program!
    Starting Price: $4.95 per month
  • 6
    RMail

    RMail

    RPost

    RMail® is the e-security platform by RPost®, a global leader since 2000. RMail specializes in elegantly easy to use email encryption for privacy and compliance, e-signatures, legal e-delivery proof, secure file sharing, email impostor protection, document rights management, and AI-infused services to prevent data leaks and human e-security errors. RMail’s transmission e-security services are most often used by businesspeople or business systems that send important, sensitive, or consumer-regulated information. These RMail services are generally applied to those messages where the sender needs functionality beyond standard email in terms of (a) easier to use and more automated email encryption for privacy compliance, (b) returning a verifiable proof record of who said what to whom by email, (c) assurance and peace of mind related to delivery and open status of important and time-deadline email, (d) need a timestamped proof of content delivered, (f) need to share large files securely.
    Starting Price: $7/month/user
  • 7
    Virtru

    Virtru

    Virtru

    Easily control access to sensitive data flowing in and out of your organization via email, file sharing, and other applications. All powered by the Trusted Data Format and Virtru’s industry-leading platform for Zero Trust Data Control. Virtru integrates natively within the apps your teams already use, securing workflows in Google, Microsoft 365, Salesforce, Zendesk, and more. We make military-grade encryption accessible to everyone. Deploy Virtru across your organization in less than a day and meet your compliance goals. Granular access controls safeguard your most valuable asset — your data — throughout its entire lifecycle, everywhere it travels. Collaborate securely in Docs, Sheets, and Slides. Store and share files in Drive. Message via Gmail and Google Meet. Secure messages flowing through enterprise and custom apps. Seamlessly protect emails and files shared via Outlook.
  • 8
    iionLife

    iionLife

    iionHealth

    iionLife by iionHealth is a free patient portal specifically created for behavioral health professionals. This effiicent and fully HIPAA secure system enables users to extend the care they deliver outside of their office. iionLife offers standardized assessment tools (i.e. PHQ-9) and a range of features for longitudinal tracking of patient results, patient journaling, activity tracking, secure email messaging, and so much more. The solution also includes Community of Care, Care Plan, Reference Library, Accounting, among others.
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