Best Endpoint Protection Software

Compare the Top Endpoint Protection Software as of January 2026

What is Endpoint Protection Software?

Endpoint protection software is a software platform that provides the solution to secure endpoints—such as laptops, desktops, smartphones, and tablets—against cyber threats and attacks. These platforms provide real-time monitoring and defense mechanisms to protect devices from malware, ransomware, phishing, and other types of threats. Endpoint protection software typically includes antivirus, anti-malware, firewall, encryption, and intrusion prevention features to prevent unauthorized access and ensure data security. It also allows for centralized management, enabling IT teams to enforce security policies, update software, and monitor the health of all devices in the network. By using endpoint protection software, organizations can safeguard their devices and networks from cyber risks while maintaining compliance with security standards. Compare and read user reviews of the best Endpoint Protection software currently available using the table below. This list is updated regularly.

  • 1
    Guardz

    Guardz

    Guardz

    Guardz is the unified cybersecurity platform purpose-built for MSPs. We consolidate the essential security controls, including identities, endpoints, email, awareness, and more, into one AI-native framework designed for operational efficiency. Our identity-centric approach connects the dots across vectors, reducing the gaps that siloed tools leave behind so MSPs can see, understand, and act on user risk in real time. Backed by an elite research and threat hunting team, Guardz strengthens detection across environments, turning signals into actionable insights. With 24/7 AI + human-led MDR, Guardz utilizes agentic AI to triage at machine speed while expert analysts validate, mitigate, and guide response, giving MSPs scalable protection without adding headcount. Our mission is simple: give MSPs the scale, confidence, and clarity they need to stay ahead of attackers and deliver protection to every SMB they serve.
    Partner badge
    View Software
    Visit Website
  • 2
    ESET PROTECT Advanced
    ESET Protect Advanced is a comprehensive cybersecurity solution designed for businesses of all sizes. It offers advanced endpoint protection against ransomware, zero-day threats, and sophisticated attacks with ESET LiveSense technology. It includes full disk encryption for legal compliance and data protection. The solution features proactive cloud-based threat defense using adaptive scanning, machine learning, cloud sandboxing, and behavioral analysis to prevent new threats. Mobile threat defense secures Android and iOS devices with anti-malware, anti-theft, and mobile device management. It also provides cloud app protection, mail server security, and vulnerability and patch management. Extended detection and response (XDR) enhances threat detection and response, while multi-factor authentication adds security. The solution offers single-pane-of-glass remote management for visibility into threats and users, along with advanced reporting and custom notifications.
    Starting Price: $275/month/5 devices
    View Software
    Visit Website
  • 3
    Heimdal Endpoint Detection and Response (EDR)
    Heimdal® Endpoint Detection and Response is our proprietary multi-solution service providing unique prevention, threat-hunting, and remediation capabilities. It combines some of the most advanced threat-hunting technologies: - Next-Gen Antivirus - Privileged Access Management - Application Control - Ransomware Encryption Protection - Patch & Asset Management - Email Security - Remote Desktop - Threat Prevention ( DNS based ) - Threat Hunting & Action Center With 9 modules working together seamlessly under one convenient roof, all within one agent and one platform, Heimdal Endpoint Detection and Response grants you access to all the essential cybersecurity layers your business needs to protect itself against both known and unknown online and insider threats. Our state-of-the-art product empowers you to quickly and effortlessly respond to sophisticated malware with stunning accuracy, protecting your digital assets and your reputation in the process as well.
    Leader badge
    Starting Price: $0/month
  • 4
    Trend Vision One

    Trend Vision One

    Trend Micro

    Stopping adversaries faster and taking control of your cyber risks starts with a single platform. Manage security holistically with comprehensive prevention, detection, and response capabilities powered by AI, leading threat research and intelligence. Trend Vision One supports diverse hybrid IT environments, automates and orchestrates workflows, and delivers expert cybersecurity services, so you can simplify and converge your security operations. The growing attack surface is challenging. Trend Vision One brings comprehensive security to your environment to monitor, secure, and support. Siloed tools create security gaps. Trend Vision One serves teams with these robust capabilities for prevention, detection, and response. Understanding risk exposure is a priority. Leveraging internal and external data sources across the Trend Vision One ecosystem enables greater command of your attack surface risk. Minimize breaches or attacks with deeper insight across key risk factors.
  • 5
    Check Point Harmony Endpoint

    Check Point Harmony Endpoint

    Check Point Software Technologies

    Check Point Harmony is the industry’s first unified security solution for users, devices and access. The solution protects devices and internet connections from the most sophisticated attacks while ensuring Zero-Trust Access to corporate applications. Protecting today’s hyper-distributed workspace requires endless security functions across user devices, applications and networks. However, stitching together point solutions often leaves security gaps and creates a cumbersome infrastructure that is difficult to manage and scale. Harmony offers an alternative that saves you the overhead and increases security. Harmony unifies 6 cloud-based security products to keep you 100% safe. Wherever you connect from, whatever you connect to, and however you connect – Your home, your devices, your privacy and your organizational data are secured and protected from any cyber threat.
  • 6
    Keplersafe

    Keplersafe

    Keplersafe

    All-in-one security with 1-click resolve that protects your entire business. A unified threat protection solution designed to bring you cutting-edge, holistic defense with zero drain on your IT resources. Our AI anticipates risk, then proactively identifies and addresses issues automatically, saving you valuable time. Keplersafe is the complete solution that makes it easy to be compliant for mid-market businesses with any sized IT or security team by helping to ensure you're protected according to best practices and accepted industry standards. The Keplersafe platform is built on the principle of holistic, non-disruptive security. Our platform employs innovative AI technology and behavioral analysis to assist businesses in staying secure and compliant, without IT teams having to worry, investigate or fix issues themselves. Keplersafe is based in New York City, with Sales and R&D offices around the globe.
    Starting Price: $8.99 per month
  • 7
    ESET PROTECT Complete
    ESET PROTECT Complete is a comprehensive cybersecurity solution designed to safeguard business endpoints, cloud applications, and email systems. It offers advanced protection against ransomware and zero-day threats through cloud-based sandboxing technology and machine learning-driven detection. It includes full disk encryption capabilities, aiding compliance with data protection regulations. ESET PROTECT Complete also provides robust security for mobile devices, file servers, and email servers, incorporating anti-malware, anti-phishing, and anti-spam measures. Its centralized, cloud-based management console allows for streamlined deployment, monitoring, and response to security incidents across the organization. Additional features include vulnerability and patch management, ensuring that software vulnerabilities are promptly identified and addressed.
    Starting Price: $287.72 one-time payment
  • 8
    ESET PROTECT Elite
    ESET PROTECT Elite is an enterprise-grade cybersecurity solution that integrates extended detection and response with comprehensive multilayered protection. It offers advanced threat defense using adaptive scanning, machine learning, cloud sandboxing, and behavioral analysis to prevent zero-day threats and ransomware. The platform includes modern endpoint protection for computers and smartphones, server security for real-time data protection, and mobile threat defense. It also features full disk encryption, helping organizations comply with data protection regulations. ESET PROTECT Elite provides robust email security, including anti-phishing, anti-malware, and anti-spam technologies, along with cloud app protection for Microsoft 365 and Google Workspace. Vulnerability and patch management capabilities allow for automatic tracking and patching of vulnerabilities across all endpoints.
    Starting Price: $275 one-time payment
  • 9
    Cynet All-in-One Cybersecurity Platform
    Cynet empowers MSPs and MSSPs with a comprehensive, fully managed cybersecurity platform that consolidates essential security functions into a single, easy-to-use solution. Cynet simplifies cybersecurity management, reduces operational overhead, and lowers costs by eliminating the need for multiple vendors and complex integrations. The platform provides multi-layered breach protection, offering robust security for endpoints, networks, and SaaS/Cloud environments. Cynet’s advanced automation streamlines incident response, ensuring rapid detection, prevention, and resolution of threats. Additionally, the platform is backed by Cynet’s 24/7 Security Operations Center (SOC), where the expert CyOps team delivers around-the-clock monitoring and support to safeguard all client environments. By partnering with Cynet, You can offer your clients advanced, proactive cybersecurity services while optimizing efficiency. Discover how Cynet can transform your security offerings today.
  • 10
    BUFFERZONE

    BUFFERZONE

    Bufferzone Security

    BUFFERZONE provides a patented containment and disarming solution that defends endpoints against advanced malware and zero-day attacks while maximizing user and IT productivity. By isolating potentially malicious content coming from browsers, email and removable media, BUFFERZONE defends individuals and organizations from advanced threats that evade detection. BUFFERZONE disarms content for securely transferring it from the container to the native endpoint and secure network zones, and provides critical intelligence for enterprise-wide security analytics. Easy to deploy and configure, BUFFERZONE is a lightweight solution that provides cost-effective containment for up to thousands of endpoints.
  • 11
    SecurityHQ

    SecurityHQ

    SecurityHQ

    SecurityHQ is a world leading independent Managed Security Service Provider (MSSP), that detects, and responds to threats, instantly. As your security partner, we alert and act on threats for you. Gain access to an army of analysts that work with you, as an extension of your team, 24/7, 365 days a year. Receive tailored advice and full visibility to ensure peace of mind, with our Global Security Operation Centres. Utilize our award-winning security solutions, knowledge, people, and process capabilities, to accelerate business and reduce risk and overall security costs. Most Popular Services: Managed Detection and Response (MDR) Endpoint Detection and Response (EDR) Managed Extended Detection and Response (XDR) Vulnerability Management Services Managed Firewall Digital Forensics & Incident Response Managed Network Detection and Response (NDR) Penetration Testing CISO as a Service
  • 12
    activeDEFENCE

    activeDEFENCE

    activereach

    From malware to advanced persistent threats (APT) to extortion & internal breaches, threats to your organisation’s infrastructure are unrelenting. Today’s businesses must consider smartphones, tablets, and consumerization of IT, combined with telecommuters, contractors, partners, and business-critical services hosted in the cloud. Security is more important than ever—and far more complex. To defend your information and systems, you need an adaptable, multi-layered defensive strategy that encompasses all the components of your IT environment, from the network to the perimeter, data, applications and endpoints, minimising and managing the weak points and vulnerabilities that expose your organisation to risk. activereach’s end-to-end portfolio of network security solutions can protect your business from advancing threats, enhance network performance, and optimise operational efficiencies.
  • 13
    Trellix XDR
    Introducing the Trellix Platform, a composable XDR ecosystem that adapts to the challenges of your business. The Trellix Platform learns and adapts for living protection while delivering native and open connections and providing expert and embedded support for your team. Keep your organization resilient with adaptive prevention that adjusts and responds in machine time to threats. Customers trust 75M endpoints to Trellix. Maximize business agility through zero trust principles and protect against front-door, side-door, and back-door attacks, all while streamlining policy management. Get comprehensive, non-invasive protection for your cloud-native applications, through secure agile DevOps and visible deployment environments. Our email and collaboration tool security protects against high-volume exposure points and attackers, automating for optimized productivity and enabling secure and agile teamwork.
  • 14
    Sealit

    Sealit

    Sealit Technologies

    When implementing a Zero Trust security model you shouldn’t question if your accounts or devices will get get compromised - assume they will. With Sealit, the sensitive data in your emails and files will remain fully protected even in that scenario. It takes one click from your existing inbox to encrypt your sensitive emails. It takes one click to encrypt any file format on your desktop. We made sure your workflow isn’t disrupted as we add a strong layer of protection to your sensitive data. Human error accounts for over 90 percent of cyber attacks on businesses, so you need to have a system in place to minimize the risk. Our patent-pending end-to-end encryption ensures each facet of your business is protected. Our app uses biometrics as authentication which provides you a seamless protection experience. Unlike passwords, biometrics cannot be taken away from you, there’s nothing you need to remember, and you always have it with you.
  • 15
    SecureAge Security Suite
    Harnessing the power of SecureData encryption technology, all your enterprise Data is protected 100% of the time with real world usability. Welcome to a seamless and non-intrusive solution for the way we work. Protection is only effective when it’s applied at the most granular level, everywhere, and all of the time. This means your Data – whether it’s on your endpoints, in your cloud service, or even with others as email. The SecureAge Security Suite offers a complete and proven solution for everyday enterprise security needs. Through time-tested technology and design, the SecureAge Security Suite achieves Data protection with a careful balance of 100% Data security, application integrity, and real-world usability. No solution works without accounting for the human element and our approach is to remove it completely. Inherent and invisible by design, our solution allows employees to work as they normally would without even thinking about cybersecurity.
  • 16
    Rotate

    Rotate

    Rotate

    Use the Rotate cloud security platform to secure any business with modular hubs and seamless integrations designed to scale your security needs. Gain greater context on cyberattacks and improve remediation by identifying alerts across all hubs, correlating them, and prioritizing incidents by risk level. Synthesize, consolidate, and manage all hubs in Rotate’s XDR. Use your multi-tenancy control center for vulnerability scans and rapid deployments. Manage unlimited clients through a single pane of glass. Empower your business customers with a complete cybersecurity solution and reduce portfolio risk. Rotate protects all types of organizations in the new world of digital-first work. Get complete cybersecurity for every employee who uses email or brings a device to work. Cyber insurance is essential for any organization at risk of a cyber attack, but coverage can be expensive. Comprehensive protection like the type provided by Rotate can help reduce the overall cost of insurance.
  • Previous
  • You're on page 1
  • Next