Verruocus Carcinoma - Clinical and histopathological features

Verruocus Carcinoma - Clinical and histopathological features

• 1.
  VERRUCOUS CARCINOMA DR DIVYAB Department of Oral Pathology & Microbiology SRM Dental College, Ramapuram, Chennai, India
• 2.
  VERRUCOUS CARCINOMA • Lowgrade variant of squamous cell carcinoma • Ackermann's tumor • Snuff dipper's cancer Department of Oral Pathology & Microbiology, SRM Dental College, Ramapuram, Chennai, India
• 3.
  CLINICAL FEATURES Exophytic, papillary pebblysurface rugae-like folds with deep clefts • Mucosal membrane - oral cavity, larynx • Site - buccal mucosa, gingiva or alveolar ridge • Male predilection • 6th - 7 th decade • Tobacco Department of Oral Pathology & Microbiology, SRM Dental College, Ramapuram, Chennai, India
• 4.
  CLINICAL FEATURES • Involvementof deeper contiguous structures • Regional lymph nodes – tender, enlarged • SYMPTOMS - Pain and difficulty in mastication Department of Oral Pathology & Microbiology, SRM Dental College, Ramapuram, Chennai, India
• 5.
  HP FEATURES Department ofOral Pathology & Microbiology, SRM Dental College, Ramapuram, Chennai, India
• 6.
  HP FEATURES • Epithelium- Well Differentiated • Shows little mitotic activity, pleomorphism, or hyperchromatism. Basement membrane intact Department of Oral Pathology & Microbiology, SRM Dental College, Ramapuram, Chennai, India
• 7.
  HP FEATURES PARAKERATIN LININGTHE CLEFTS WITH PARAKERATIN PLUGGING Department of Oral Pathology & Microbiology, SRM Dental College, Ramapuram, Chennai, India
• 8.
  DISTINGUISHING FEATURES FEATURES VERRUCOUSCARCINOMA OSCC Mode of growth Slow Rapid Metastatic potential Low High Prognosis Better poor Department of Oral Pathology & Microbiology, SRM Dental College, Ramapuram, Chennai, India
• 9.
  TREATMENT • Conservative excision •Patients treated by ionizing radiation - anaplastic transformation of lesions Department of Oral Pathology & Microbiology, SRM Dental College, Ramapuram, Chennai, India
• 10.
  THANK YOU Department ofOral Pathology & Microbiology, SRM Dental College, Ramapuram, Chennai, India