This document discusses several types of natural plant compounds that act as insect deterrents or toxins, including alkaloids, DMDP, and glucosinolates. Alkaloids are a diverse group of nitrogen-containing compounds found in over 20% of flowering plant species that interfere with acetylcholine transmission in insects. DMDP is a potent inhibitor of insect alpha-glucosidase found in Derris and Lonchocarpus plants that is toxic to insects like seed beetles and locust nymphs at low concentrations. Glucosinolates are sulfur-containing compounds in plants like crucifers that appear to provide effective defense against most non-adapted herbivorous insects.